Skip to main page content home current archive collections 中国 (abstracts) radiology select radiographics rsna. cheap viagra online Org search go advanced search user name password sign in the eye-of-the-tiger sign1 r. Paul guillerman , md 1from the department of radiology, children’s hospital medical center, 3333 burnet ave, cincinnati, oh 45229-3039. Received may 12, 1999; accepted july 13. viagra amazon co uk Address correspondence to the author (e-mail: guilr0@chmcc. cheap generic viagra Org). â  next section appearance on t2-weighted magnetic resonance (mr) images, marked low signal intensity circumscribes the globus pallidus. This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, producing an eye-of-the-tiger appearance (figure) (1). The central region of high signal intensity may be better appreciated with certain pulse sequences (2). View larger version: in this window in a new window download as powerpoint slide figure 1. Transverse t2-weighted mr image depicts a low-signal-intensity ring (arrow) surrounding a central high-signal-intensity region (arrowhead) in the medial aspect of the globus pallidus, producing an eye-of-the-tiger appearance. Previous section next section explanation the eye-of-the-tiger sign is most commonly described in hallervorden-spatz syndrome, where the ring of marked hypointensity involving the globus pallidus on t2-weighted mr images is due to excess iron accumulation. the price of viagra Iron is absent from the central nervous system at birth, but deposits occur throughout life in healthy adults, with the highest concentrations occurring in the globus pallidus primarily in the form of the metalloprotein ferritin (3,4). This iron deposition is pathologically intensified in hallervorden-spatz syndrome, while iron levels in blood and cerebrospinal fluid remain normal (5). viagra boots 2011 Superparamagnetic iron substances such as ferritin have unpaired orbital electrons, which result in positive magnetic susceptibilities, a decrease in t2, and low signal intensity on t2-weighted images (6). buy generic viagra Calcium deposition does not appear to be a substantial contributor to the basal ganglionic mineralization process in hallervorden-spatz syndrome (2). lowest price for generic viagra The central high signal intensity of the globus pallidus in hallervorden-spatz syndrome has been attributed to gliosis, increased water content, and neuronal loss with disintegration, vacuolization, and cavitation of the neuropil (1,2,7,8). These processes lengthen t2, which produces high signal intensity on t2-weighted images. Previous section next section discussion the term hallervorden-spatz syndrome encompasses several disorders, each of which shares the clinical features of progressive extrapyramidal dysfunction and dementia with the pathologic triad of iron deposition, axonal spheroids, and gliosis in the globus pallidus (9). Hallervorden-spatz disease is the familial pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia (10). buy viagra online Other. the price of viagra viagra use agent Bienvenidos a la web de la Liga de BB
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